Like felines, ferrets can be litter prepared. In any case, for the best probability of triumph, it’s indispensable to acquaint them with a litter box as fast as could reasonably be expected. Being amicable does not come common to a ferret, but rather they can be prepared to be well disposed with some instructing. Teaching them requires that you start acquainting them with people at 30 days of age. The more you handle them the more they can get to know you and build up an affection for you. Watch video in link below
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The way to an effective ferret environment is to sustain their interest while at the same time shielding them from it, and that requires wellbeing, supervision, recess, and toys
Supervision is vital. I am a firm devotee to confining my ferrets when I am sleeping or not at home. Their confine is huge and has different levels. I change their bedding once per week (or increasingly if justified). I clean their litter boxes every day.